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June 2009

Experts urge stronger limits for some pain drugs (Reuters)

ADELPHI, Maryland (Reuters) –
Prescription painkillers that include acetaminophen should be pulled from the U.S. market because they can make it too easy for patients to take dangerously high doses, a government advisory panel narrowly recommended on Tuesday.

A U.S. Food and Drug Administration panel of outside experts voted 20-17 to urge the agency to eliminate such products, which include, among others, Abbott Laboratories' Vicodin and Endo Pharmaceuticals' Percocet -- two drugs that combine acetaminophen with powerful opioids.

"This is clearly the biggest cause of overdose problems," said panelist Dr. Marie Griffin, a preventive medicine professor at Vanderbilt University Medical Center.

The recommendation is one of several from the panel, which is weighing potential steps the agency can take to help prevent liver damage and even death seen in patients who take too much acetaminophen.

Overdoses of acetaminophen, most commonly known as Johnson & Johnson's Tylenol, have long been known to cause liver failure and even death.

Acetaminophen use is the leading cause of acute liver failure in the 1,600 cases seen each year in the United States, according to a 2007 Centers for Disease Control and Prevention estimate.

FDA officials are concerned that warnings are not heeded by consumers and are looking for new ways to reduce the number of overdoses. The agency will weigh the panel's recommendations before making any final decisions.

Other makers of acetaminophen, or products that contain it, include Bayer AG, GlaxoSmithKline, Novartis, Perrigo Co, Procter & Gamble, Schering-Plough and Wyeth.

The panel stopped short of recommending a ban of over-the-counter cough, cold and other medications that combine acetaminophen with other ingredients, voting 24-13 to keep them on store shelves.

Still, it said over-the-counter pain drugs and other medications containing acetaminophen should come in lower doses and that the highest dose currently on the market should only be available with a doctor's prescription.

Johnson & Johnson's McNeil Consumer Healthcare unit, which makes Tylenol, said it strongly disagreed with that advice and that its products are safe. Changing dose strengths was "likely to lead to more serious adverse events as consumers shift to other over-the-counter products such as non-steroidal anti-inflammatory drugs," it said in a statement.

Those anti-inflammatory painkillers, also known as NSAIDs, which include aspirin and ibuprofen, are know to cause stomach bleeding. The FDA earlier this year called for stronger warnings for both NSAIDS and acetaminophen products to highlight the stomach and liver risks.

At the meeting, panelists also said additional changes to product packaging, including graphics, could also help alert consumers to the risks.

"I think we have to send the message that there are problems with this medication," said Winifred Landis, a pharmacist from Indiana.

(Reporting by Susan Heavey; Editing by Tim Dobbyn and Steve Orlofsky)

Grand Piano Covers

Grand pianos have the frame and strings placed horizontally, with the strings extending away from the keyboard. This makes the grand piano a large instrument, for which the ideal setting is a spacious room with high ceilings for proper resonance. There are several sizes of grand piano. Manufacturers and models vary, but a rough generalization distinguishes the "concert grand" (between about 2.2 m to 3 m long) from the "parlor grand" (about 1.7 m to 2.2 m) and the smaller "baby grand" (which may be shorter than it is wide).

A relatively recent development is the prepared piano, which is used in contemporary art music. A prepared piano is a standard grand piano which has had objects placed inside it before a performance in order to alter its sound, or which has had its mechanism changed in some way. The scores for music for prepared piano often instruct the pianist to insert pieces of rubber or small pieces of metal (screws or washers) in between the strings. These added items either mute the strings or create unusual vibrating sounds.

Grand Piano Covers

Yemeni plane with 153 crashes off Comoros islands (AP)

MORONI, Comoros – A Yemeni jetliner carrying 153 people crashed into the Indian Ocean on Tuesday as it attempted to land amid severe turbulence and howling winds. Officials said a teenage girl was plucked from the sea, the only known survivor.
The crash in waters off this island nation came two years after aviation officials reported equipment faults with the plane, an aging Airbus 310 flying the last leg of a Yemenia airlines flight from Paris and Marseille to Comoros, with a stop in Yemen to change planes.
Most of the passengers were from Comoros, a former French colony. Sixty-six on board were French nationals.
Khaled el-Kaei, the head of Yemenia's public relations office, said a 14-year-old girl survived the crash, and Yemen's embassy in Washington issued a statement saying a young girl was taken to a hospital. It also said five bodies were recovered.
Sgt. Said Abdilai told Europe 1 radio that he rescued the girl after she was found bobbing in the water. She couldn't grasp the life ring rescuers threw to her, so he jumped into the sea, Abdilai said. He said rescuers gave the trembling girl warm water with sugar.
There were earlier statements from officials that a 5-year-old boy survived. El-Kaei said that was not known and the airline had lost contact with its office in Comoros because of bad weather.
Yemeni civil aviation deputy chief Mohammed Abdul Qader said the flight data recorder had not been found and it was too early to speculate on the cause of the crash. But he said winds in excess of 40 miles per hour were pummeling the plane as it was landing in darkness in the early morning hours Tuesday.
Turbulence was believed to be a factor in the crash, Yemen's embassy in Washington said.
"The weather was very bad," Qader said, adding the windy conditions were hampering rescue efforts.
The Yemenia plane was the second Airbus to crash into the sea this month. An Air France Airbus A330-200 crashed into the Atlantic Ocean on June 1, killing all 228 people on board, as it flew from Rio de Janeiro to Paris.
Mohammed Moqbel, a Yemeni pilot who has flown to the Comoros, said the route can be difficult because of the geography and weather.
"The airport is also very poor in terms of equipment," said Moqbel. "They don't have advanced radars to guide planes."
The tragedy — and dwindling hopes that anyone else made it out alive — prompted an outcry in the Comoros, where residents complained of a lack of seat belts on Yemenia flights and planes so overcrowded that passengers had to stand in the aisles.
The Comoros, a former French colony of 700,000 people, is an archipelago of three main islands situated 1,800 miles south of Yemen, between Africa's southeastern coast and the island of Madagascar.
Gen. Bruno de Bourdoncle de Saint-Salvy, the senior commander for French forces in the southern Indian Ocean, said the Airbus 310 crashed in deep waters about nine miles north of the Comoran coast and 21 miles from the Moroni airport. Searchers encountered an oil slick at the site, the Yemeni Embassy statement said.
French aviation inspectors found a "number of faults" in the plane's equipment during a 2007 inspection, French Transport Minister Dominique Bussereau said on France's i-Tele television Tuesday. He did not elaborate
In Brussels, European Union Transport Commissioner Antonio Tajani said the airline had previously met EU safety checks and was not on their blacklist. But he said a full investigation was being launched amid questions about why the passengers — who originated in Paris — were transferred on another jet in the Yemeni capital of San'a.
An Airbus statement said the plane that crashed went into service 19 years ago, and had accumulated 51,900 flight hours. It has been operated by Yemenia since 1999. Airbus said it was sending a team of specialists to the Comoros.

The A310-300 is a twin-engine widebody jet that can seat up to 220 passengers. There are 214 A310s in service worldwide, with 41 operators.

A crisis center was set up at Charles de Gaulle Airport in Paris. Many passengers were from the French city of Marseille, home to around 80,000 immigrant Comorans, more even than Comoros' capital of Moroni.

Yemenia has long been a target of criticism for the poor condition of its passenger cabins, with recent passenger complaints about missing or faulty seat belts.

Still, analysts have cautioned against equating the condition of the passenger cabin on any airline with the aircraft's maintenance records.

Yemenia airways has a solid safety record. In 2008 it passed the International Airline Transport Association's operational safety audit, a rigorous set of inspections considered an indication of high quality for any airline.

One problem that does crop up with older aircraft, particularly when a certain model has been discontinued, is the issue of fake replacement parts, experts said.

Airline companies sometimes unwittingly purchase fake parts, which are then put into aircraft by their maintenance crews. Despite rigorous international efforts to root out counterfeit spares in the past decade, they are still believed to be in circulation.

"Pirate spare parts remain a big maintenance problem in aviation," said Capt. Harry Eggerschwiler, chief of operations for the African Civil Aviation Authority. "This is true everywhere in the world and not just in (developing) countries."

Some French Comorans insisted their complaints about the airline's safety weren't heeded by authorities.

Zalifa Youssouf, a member of SOS Voyages, which seeks to improve passenger conditions and safety, told France's i-Tele television that the Comoran community had complained about the flight from San'a to Comoros.

She said the planes were dirty, frequently did not have safety belts and that flight attendants often did not speak French, just Arabic which passengers did not understand. "We felt we were in danger," Youssouf said.

Mohamed Ali, a Comoran who went to Yemenia's headquarters in Paris to try to get more information about the doomed flight, said complaints about safety went unheeded. "Some people stand the whole way to Moroni," he said.

In France, school vacations began this week and many on the plane were heading home to visit.

Christophe Prazuck, French military spokesman, said a patrol boat and reconnaissance ship were sent to the crash site as well as a military transport plane. The French were sending divers as well as medical personnel, he said.

Yemenia airline officials said the 11-member crew was made up of six Yemenis, including the pilot, two Moroccans, an Indonesian, an Ethiopian and a Filipino.

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Al-Haj contributed to this report from San'a, Yemen. Associated Press writers Deborah Seward, Angela Charlton and Greg Keller in Paris, Sarah El Deeb in Cairo and Yoann Guilloux in Saint-Denis de la Reunion, Reunion Island, contributed to this report.

Curry sacked as Pistons coach after one year (Reuters)

DETROIT (Reuters) –
Michael Curry was sacked as Detroit Pistons coach on Tuesday after just one season in charge.

"This was a difficult decision to make," said Joe Dumars, Pistons president of basketball operations in a statement on the team's website (www.nba.com/pistons).

"I want to thank Michael for his hard work and dedication to the organization. However, at this time, I have decided to make a change."

Under Curry the Pistons finished with a regular-season record of 39-43 and advanced to the playoffs where they were swept from the first round in four games by the Cleveland Cavaliers.

The results fell far short of the high expectations for a team that had reached the conference finals the previous six years.

A former Pistons player, Curry watched the season unravel following an unpopular trade in which popular point guard Chauncey Billups moved to the Denver Nuggets in exchange for Allen Iverson.

While Billups revived the Nuggets, Iverson flopped in Detroit and ended the season on the injury list.

(Writing by Steve Keating in Toronto; Editing by Ed Osmond)

Fans gather for Apollo Theater's Jackson memorial (AP)

NEW YORK – Hundreds of Michael Jackson fans circled the block around Harlem's famed Apollo Theater Tuesday for a public tribute to the pop star, some spontaneously singing their favorite songs and dancing in the street.
"I thought that in my time I'd have the opportunity to see him in concert," said Victoria Campomames, who did a brief moonwalk on the sidewalk as "Rock With You" played from a nearby store. "This is about the closest I'm gonna get."
Campomames, wearing a Jackson-style spangled black jacket, fedora and white gloves, took the day off from her job at a grocery store in Morrisville, Vt., for the all-day tribute to Jackson at the fabled venue that helped make him a star.
Thousands were expected to pay their respects at the theater, which planned to let them in 600 at a time to listen to his music, watch a video tribute and leave flowers and memorabilia.
The event was set to start at 2 p.m., but many people were already waiting Tuesday morning, dancing as they lined up with T-shirts, posters, album covers and other mementoes.
Ebony Johnson, 19, arrived at midnight to secure a spot near the front of the line, clutching a Jackson scrapbook she started when she was 14. An image of the star was tattooed on her left arm. She said she got the tattoo last month in anticipation of his planned comeback shows in London.
"I love him so much — I can't explain that in words," she said. "I felt like Michael was my family."
Fans wrote messages on a wall of remembrance outside the 125th street theater. "God bless and be with you M. Jackson," wrote one fan. "We all share your grief. Love always," read a message to his family.
Fans began converging on the Apollo soon after Jackson died Thursday in Los Angeles. It has continued to serve as an impromptu memorial site in the days since.
The pop icon's ties to the theater go back to 1967, when The Jackson 5 won the Apollo's Amateur Night contest. The appearance is credited with helping to launch the brother act's career, which later propelled Jackson to solo stardom.
Jackson last appeared at the Apollo in 2002, invited by former President Bill Clinton for a Democratic National Committee fundraiser.
Tuesday's salute was to begin with a eulogy by the Rev. Al Sharpton. A moment of silence was planned for 5:26 p.m., the time East Coast fans learned that Jackson had died.
The Apollo also played a role in remembrances for James Brown after his death in 2006, hosting a public viewing of the "Godfather of Soul" for thousands of fans.

GM CEO makes case for bankruptcy asset sale (Reuters)

NEW YORK (Reuters) –
General Motors Corp's chief executive told a U.S. bankruptcy court on Tuesday that the sale of GM's main assets to government-backed "New GM" must win court approval in order for the iconic automaker to survive.

Fritz Henderson told the court that if the sale is not approved by July 10 and GM loses access to government funding, the company would be forced to liquidate. He testified on the first day of a hearing at which the automaker is seeking court approval for the sale just 30 days after filing for Chapter 11.

"Business is doing better" at GM, Henderson said, as customers, suppliers, workers and others anticipate the completion of a successful deal. He added that the automaker had originally hoped to repay its loans to the government and restructure outside of bankruptcy.

Henderson also discussed the ouster of former GM CEO Rick Wagoner, saying that Wagoner told him that he had been asked to step down by Steve Rattner, head of the Obama administration's autos task force.

The GM sale hearing, before Judge Robert Gerber, is expected to continue for at least two days, as the company faces objections and questions from its creditors committee, a group of dissenting bondholders, those with liability and asbestos claims against the company, as well as unions and dealerships.

A lawyer for GM, Harvey Miller of Weil Gotshal & Manges, opened the proceeding by noting the company had made progress on some of the objections about tort claims and state tax claims, but that others were still unresolved.

If the deal is approved, GM will be able to sell its best assets, including Chevrolet and Cadillac, under Section 363 of the bankruptcy code to a "New GM" while the U.S. Treasury would provide billions of dollars in financing.

GM's old assets would remain behind in bankruptcy court to be liquidated.

BIG WIN FOR U.S. AUTOS TASK FORCE

A successful sale would mark the second big victory for the Obama administration's autos task force, which earlier this month also helped broker the sale of Chrysler LLC to a group led by Italy's Fiat SpA. The U.S. Supreme Court cleared the way for that deal to go through on June 9.

Outside the Manhattan courthouse, about 75 union-affiliated protesters carried placards and chanted "Save our benefits."

No competing bidders have emerged as an alternative to the U.S. government's $60 billion financing for GM, including a proposed equity investment of $50 billion that would give the U.S. Treasury a 60 percent ownership stake.

Under the plan, the United Auto Workers union would gain a 17.5 percent stake in New GM, the Canadian government would own about 12 percent, and GM bondholders are expected to get about 10 percent.

GM has said more than 50 percent of its bondholders support the deal, but a group of small bondholders mounted a challenge to the sale in court on Tuesday.

Several other individual bondholders have filed objections to the sale, along with the state of Texas which contends the sale illegally challenges state laws on dealerships, and a group representing about 300 Americans with lawsuits against GM for alleged product defects.

GM, however, resolved a key objection from nine state attorneys general over the weekend, saying New GM would accept liability for future product defects. The company also said it would address objections raised by more than 20 of its parts suppliers.

The case is In re: General Motors Corp, U.S. Bankruptcy Court, Southern District of New York, No. 09-50026.

(Reporting by Emily Chasan and Caroline Humer, editing by Matthew Lewis)

`Thriller' viewed 8.5 million times since Thursday (AP)

NEW YORK – People are clamoring to see Michael Jackson's old videos in the wake of his death — especially "Thriller."
On Tuesday, Internet video research firm Visible Measures, said Jackson's most famous music video has been watched more than 8.5 million times online since his death Thursday.
Visible Measures, which counts Internet-wide video traffic, also factored in other versions of "Thriller," including the dance video produced by Filipino prisoners.
While many of Jackson's videos have been popular, the 14-minute John Landis-directed "Thriller," made in 1983, is his most famous.

Man allegedly drenches wife with hose for smoking (AP)

JENSEN BEACH, Fla. – Authorities said a man has been charged with domestic battery after he drenched his wife with a garden hose and elbowed her for smoking in the house. An arrest report shows that the 51-year-old husband was charged Saturday. Police said the couple began arguing when the wife began smoking a cigarette in their home.
When the victim picked up the phone and began calling a friend, authorities said the husband believed she was trying to call police and elbowed her in the mouth during a struggle to grab the phone.
The woman was soaked with water when deputies arrived. The husband told deputies he had been watering the grass and did not intend to spray her.
The man was taken to the Martin County Jail and released after posting bond.
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Information from: The Stuart News, http://www.tcpalm.com

Minnesota court rules Democrat Al Franken won Senate seat (Reuters)

MINNEAPOLIS (Reuters) –
The Minnesota Supreme Court on Tuesday declared Democrat Al Franken the winner of a tight Senate race over Republican Norm Coleman, effectively giving Democrats a critical 60-seat majority needed to push through President Barack Obama's agenda.

Coleman told reporters in St Paul, Minnesota: "I will abide by (the court's) result."

Under state law, the court's decision gives Franken, a well-known satirist and a former writer and actor for the popular Saturday Night Live television show, the right to occupy the seat.

The vote count was the subject of recounts and legal battles since last November's election.

Minnesota Republican Governor Tim Pawlenty has said he would certify the election winner based on what the state court decides. Pawlenty, considered a possible presidential contender in 2012, said he would not run for governor again next year, which clears an avenue for Coleman to run for governor.

The Minnesota court, in its 32-page ruling, knocked down each of Coleman's five legal arguments that an earlier vote recount had been unfair.

The court said Franken was "entitled" to the certificate of election, which must be signed by Pawlenty and Minnesota's Secretary of State, Democrat Mark Ritchie.

Democrats will now control 60 of the 100 Senate seats -- enough to overcome Republican procedural roadblocks.

However, Senate Democrats may not be able to rely on the votes of some members, including Arlen Specter, the former Republican from Pennsylvania who switched parties in April. Specter has said he will vote his own way and not necessarily along party lines.

SEE-SAW RACE

Coleman, seeking a second term, held a razor-thin 206-vote lead in initial results after the November 4 election.

But the close vote triggered an automatic recount of the 2.4 million ballots cast for the two men, and Franken edged to a 225-vote lead. That was challenged by Coleman and a judicial panel agreed to add only a few hundred previously rejected absentee ballots. That tally expanded Franken's lead to 312.

Franken would be the 58th Senate Democrat, the most the party has had since 1981. They could muster the 60 votes needed to clear Republican procedural hurdles known as filibusters -- provided all Democrats stick together and are joined by two independents who routinely vote Democratic.

The last time either party had a filibuster-proof 60 was 1979 when Democrats held 61 and Democratic Jimmy Carter was president.

Gaining the 60 Senate votes could help President Barack Obama move his ambitious agenda through the chamber, and thus Congress. Democrats also control the House of Representatives, 256 to 178 with one vacancy.

There is no guarantee Senate Democrats would all fall in line to pass Obama's top initiatives, and the Democratic president knows it.

"I am under no illusions that suddenly I'm going to have a rubber-stamp Senate," Obama said in April after Specter switched parties.

"I've got Democrats who don't agree with me on everything, and that's how it should be," the president said.

The Franken-Coleman duel was the longest contested Senate election since a 1974 New Hampshire race, which was voided 10 months later due to voting irregularities, according to the Senate historian's office.

(Additional reporting by Tom Ferraro in Washington; Writing by Andrew Stern; Editing by David Storey)

Source: Suspected NKorean ship changes course (AP)

WASHINGTON – U.S. officials said Tuesday that a North Korean ship has turned around and is headed back toward the north where it came from, after being tracked for more than a week by American Navy vessels on suspicion of carrying illegal weapons.
The move keeps the U.S. and the rest of the international community guessing: Where is the Kang Nam going? Does its cargo include materials banned by a new U.N. anti-proliferation resolution?
The ship left a North Korean port of Nampo on June 17 and is the first vessel monitored under U.N. sanctions that ban the regime from selling arms and nuclear-related material.
The Navy has been watching it — at times following it from a distance. It traveled south and southwest for more than a week; then, on Sunday, it turned around and headed back north, two U.S. officials said on condition of anonymity to discuss intelligence.
Nearly two weeks after the ship left North Korea, officials said Tuesday they still don't know where it is going. But it was some 250 miles south of Hong Kong on Tuesday, one official said.
Though acknowledging all along that the Kang Nam's destination was unclear, some officials said last week that it could be going to Myanmar and that it was unclear whether it could reach there without stopping in another port to refuel.
The U.N. resolution allows the international community to ask for permission to board and search any suspect ship on the seas. If permission for inspection is refused, authorities can ask for an inspection in whichever nation where the ship pulls into port.
North Korea has said it would consider any interception of its ships a declaration of war.
Two officials had said earlier in the day Tuesday that the Kang Nam had been moving very slowly in recent days, something that could signal it was trying to conserve fuel.
They said they didn't know what the turnaround of the ship means, nor what prompted it.
The U.S. ambassador to the United Nations, Susan Rice, said Sunday that Washington was "following the progress of that ship very closely," but she would not say whether the U.S. would confront the Kang Nam.
The sailing of the vessel — and efforts to track it — set up the first test of a new U.N. Security Council resolution that authorizes member states to inspect North Korean vessels. The sanctions are punishment for an underground nuclear test the North carried out in May in defiance of past resolutions.
Meanwhile on Tuesday, the Obama administration imposed financial sanctions on a company in Iran that is accused of involvement in North Korea's missile proliferation network.
In the latest move to keep pressure on Pyongyang and its nuclear ambitions, the Treasury Department moved against Hong Kong Electronics, a company located in Kish Island, Iran. The action means that any bank accounts or other financial assets found in the United States belonging to the company must be frozen. Americans also are prohibited from doing business with the firm.